Iron Metabolism in Humans: An Overview
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چکیده
1. When iron was available some 10 billion years ago, it was available as Fe (II), but Fe (II) is not a very strong Lewis acid. Thus, it does not bind strongly to most small molecules or activate them strongly toward reaction. 2. Today iron is not readily available from sea or water solutions due to oxidation and hydrolysis. 3. Iron in ferrous state is not easily retained by proteins since it does not bind very strongly to them. 4. Free Fe (II) is mutagenic, especially in the presence of dioxygen.
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تاریخ انتشار 2012